Now showing items 1-3 of 3
Murine Phenotype Analyses and the Role of TRPV1 in Hypoxia
The environment in which animals are maintained is a factor that has the potential to alter the physiologic phenotype. We addressed the hypothesis that the standard animal care (SAC) environment cause significant deviations ...
An In Vitro Murine Model to Study Intestinal Mesenteric Afferent Activity in Response to Luminal Fatty Acid Stimuli
Obesity is pandemic. Pharmacological treatment development depends on modeling the regulation of feeding, particularly by free fatty acids (FFA). Most models have been employed in the rat in vivo, and show FFA-stimulated ...
Neural Regulation in Circular Smooth Muscle of Mouse Lower Esophageal Sphincter
The lower esophageal sphincter (LES) is characterized by basal tone and appropriately timed neurogenic relaxation. The physiological mechanisms underlying these crucial LES functions remain poorly understood. The current ...