Now showing items 1-5 of 5
Regulation of the Human Ether-à-Go-Go-Related Gene (hERG) Channel by RAB4 Through Neural Precursor Cell-Expressed Developmentally Downregulated Protein 4-2 (NEDD4-2)
The human ether-à-go-go-related gene (hERG) encodes the pore-forming α-subunits of the Kv11.1 channel that is responsible for the cardiac rapidly activating delayed rectifier K+ current (IKr), which plays a critical role ...
The Serum-‐ and Glucocorticoid-‐Inducible Kinase SGK1 and SGK3 Regulate hERG Channel Expression via Ubiquitin Ligase Nedd4-‐2 and GTPase Rab11
The rapidly activating delayed rectifier potassium channel (IKr) encoded by the human ether-a-go-go related gene (hERG) is a crucial component of cardiac repolarization of the action potential. ...
Febrile Temperature Facilitates Degradation of Human Ether-a-Go-Go-Related Gene (hERG) Channels
The human ether-a-go-go-related gene (hERG) encodes the α subunit of the rapidly activating delayed rectifier K+ channel (IKr), which plays an essential role in human cardiac repolarization. Dysfunction of hERG caused by ...
Regulation of the Human Ether-a-go-go Related Gene Potassium Channel by Neural Precursor Cell Expressed Developmentally Down-regulated Protein 4-2 Interacting Proteins
Dysfunction of the human ether-a-go-go related gene (hERG)-encoded rapidly activating delayed rectifier K+ channel is a major cause of long QT syndrome (LQTS) due to its critical role in the repolarization of cardiac action ...
Cardiac Potassium Channel hERG is Rregulated by Ubiquitin Ligase Nedd4-2
The cardiac rapidly activating delayed rectifier potassium channel (IKr) is encoded by the human ether-a-go-go related gene (hERG), which is important for repolarization of the cardiac action potential. Reduction in hERG ...