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Role of Stromal Cell-Derived Factor-1 in Neoangiogenesis in Endometriosis Lesions
Endometriosis affects 5-10% of women and is characterized by the growth of endometrial tissue outside of the uterus. Treatment for endometriosis primarily focuses on symptom relief, is short term with severe side effects ...
Peptide inhibitors of angiogenesis in endometriosis and the female reproductive system
Endometriosis, characterized by the growth of endometrium outside the uterine cavity, is a disease which causes pelvic pain, inflammation and associated with infertility. Endometrium, which exits the uterus through retrograde ...
Thrombospondin-1 Analog, ABT-898, Inhibits Endometriotic Lesion Vascularization Without Affecting Fertility or Pregnancy Outcomes in a Murine Model of Endometriosis
Endometriosis is a gynecological disease defined as the growth of endometrium outside of the uterus. Although linked to 50% of female infertility cases, current medical treatments fail to maintain fecundity. Since the ...
Mouse Uterine Natural Killer Cell Functions During Early Pregnancy
Early pregnancy is characterized by complex interactions between blood vessels, leukocytes, and conceptus-derived trophoblasts within the gestational uterus. Uterine Natural Killer (uNK) cells become the most abundant ...