Now showing items 1-4 of 4
A Functional, Comparative and Clinical Analysis of Sperm-Borne Oocyte Activating Factor, PAWP
Successful fertilization depends upon the activation of metaphase II arrested oocytes by sperm-borne oocyte activating factor (SOAF). Failure of oocyte activation is considered as the cause of treatment failure in a ...
The Identification and Characterization of an Inner Acrosomal Membrane Associated Protein, IAM38, Responsible for Secondary Sperm-Zona Binding During Fertilization
During mammalian fertilization, the exposure of the inner acrosomal membrane (IAM) after acrosomal exocytosis is essential for the secondary binding between sperm and zona pellucida (ZP) of the oocyte, a prerequisite for ...
Contribution of a Sperm Protein, PAWP, to the Signal Transduct Pathway During Vertebrate Fertilization
PAWP, postacrosomal sheath WW domain binding protein, is a novel sperm protein identified as a candidate sperm borne, oocyte-activating factor (SOAF). PAWP induces both early and later egg activation events including meiotic ...
Identification and Development of Enzymes Associated With the Sperm Inner Acrosomal Membrane and Their Function During Fertilization
In order for mammalian fertilization to transpire, spermatozoa must transit through the female reproductive tract and penetrate the outer investments of the oocyte: the cumulus oophorus and the zona pellucida. In order ...