Now showing items 1-4 of 4
The Role of Abnormal Maternal Inflammation in the Pathogenesis of Pregnancy Complications
Pre-eclampsia (PE), fetal growth restriction (FGR) and fetal death are common complications associated with human pregnancy. A hallmark of these adverse pregnancy outcomes is reduced utero-placental perfusion, which is ...
Abnormal inflammation in a rat model of spontaneous fetal loss leads to maternal coagulopathies associated with placental haemostatic alterations
Spontaneous foetal loss is the most common complication of pregnancy, affecting up to 20% of recognized pregnancies and recurring in 1-3% of cases. Abnormal maternal inflammation and systemic maternal coagulopathies are ...
Transient Lipopolysaccharide-Induced Cytokine Responses in the Maternal and Fetal Guinea Pig
The aim of this study was to further investigate the role of pro-inflammatory cytokines in the pathogenesis of fetal cererbral white matter injury associated with chorioamnionitis by charaterizing the time course of the ...
Investigation of the effect of intrauterine inflammation and infection on fetal brain injury using human and animal models
In recent years, increased focus has been placed on the role of intrauterine infection and inflammation in the pathogenesis of fetal brain injury leading to neurodevelopmental disorders such as cerebral palsy. At present, ...